عنوان فارسی مقاله: اپی ژنتیک


عنوان انگلیسی مقاله:

Epigenetics






 

فهرست مطالب

Epigenetics

Three main players

Chromatin

Histone modifications on the nucleosome core particle

Histone modifications determine function

Examples of the “histone code” for H3/H4

Histone tail modifications alter chromatin accessiblity

Histone modifying complexes and nucleosome remodeling complexes recognize the modified histones through specific domains

Is there a histone code?

Spreading of an epigenetic mark and remodelling

Are the histone modifications really epigenetic and thus heritable?

Inheritance of histones after DNA replication

DNA Methylation

Role of methylation in silencing

DNA methylation patterns differ between stem cells and differentiated cells

DNA methylation lies at the heart of Imprinting

RNA meets Chromatin

Short RNAs (21-23 nt) direct silencing of genes in three different ways

Overview

Core features of miRNA and siRNA silencing

Synopsis




بخشی از مقاله

Core features of miRNA and siRNA silencing

In general:

– miRNAs- regulators of endogenous genes

– siRNAs- defenders of genome integrity in response to foreign or invasive nucleic acids such as viruses, transposons, and transgenes. 

Single-stranded forms of both miRNAs and siRNAs are found to associate with effector assemblies known as RNA-induced silencing complexes (RISCs).







 

کلمات کلیدی: 

Epigenetics - Learn Genetics (Utah) learn.genetics.utah.edu/content/epigenetics/ Epigenetics is the study of these chemical reactions and the factors that influence them. video. The Epigenome at a Glance. Meet the epigenome and learn how ... Epigenetics & Inheritance - Learn Genetics (Utah) learn.genetics.utah.edu › Epigenetics We used to think that a new embryo's epigenome was completely erased and rebuilt from scratch. But this isn't completely true. Some epigenetic tags remain in ... Epigenetic Influences and Disease | Learn Science at Scitable - Nature www.nature.com/scitable/topicpage/epigenetic-influences-and-disease-895 by D Simmons - ‎2008 - ‎Cited by 52 - ‎Related articles Provides introductory information on epigenetics and its association to diseases. Epigenetics: The sins of the father : Nature News & Comment www.nature.com/news/epigenetics-the-sins-of-the-father-1.14816 Mar 5, 2014 - Biologists first observed this 'transgenerational epigenetic inheritance' in plants. Tomatoes, for example, pass along chemical markings that ... Epigenetics 101: a beginner's guide to explaining everything | Cath ... https://www.theguardian.com › Science › Genetics Apr 25, 2014 - Cath Ennis: The word 'epigenetics' is everywhere these days, from academic journals and popular science articles to ads touting miracle cures. Searches related to Epigenetics epigenetics examples epigenetics labs epigenetics psychology epigenetics for dummies epigenetics inheritance epigenetics diet epigenetics trauma epigenetics international