عنوان فارسی مقاله: مکانیسم های آنزیم


عنوان انگلیسی مقاله:

Enzyme Mechanisms






 

فهرست مطالب

Enzyme Mechanisms

Questions

Mechanisms

Binding Energy

Effective Molarity

Induced Fit

Lowering Activation Energy

Weak Binding of Substrate

Transition State Binding

Designing a Transition State Analog

Binding of Transition State Analog

Binding Catalysis and …

…Chemical Catalysis

General Acid-Base Catalysis

Covalent Catalysis

pH affects Enzyme Catalysis

Case Study: Diffusion Controlled Enzymes

Triose Phosphate Isomerase

Mechanism

Superoxide Dismutase:  Better than Diffusion!

Answers





بخشی از مقاله

Questions

1. Replacement of the amino acid ________ at or near an active site of an enzyme is more likely to change enzyme activity than the replacement of ________ at or near the active site.

A) histidine; leucine

B) leucine; histidine

C) leucine; isoleucine

D) histidine; aspartate


2. The following pH dependence was found for the activity of a certain enzyme-catalyzed reaction. If it is known that the only two ionizable residues in the active site are both glutamates, which conclusion can be drawn? 

A) The glutamates have different microenvironments which cause their pKa's to differ. 

B) One of the glutamates must be amidated. 

C) Both glutamates have a pKa equal to 5.0. 

D) Both glutamates are deprotonated during the reaction. 








 

کلمات کلیدی: 

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